Comparative effectiveness of efavirenz-based antiretroviral regimens in resource-limited settings
نویسندگان
چکیده
منابع مشابه
Effectiveness of Efavirenz-Based Regimens in Young HIV-Infected Children Treated for Tuberculosis: A Treatment Option for Resource-Limited Settings
BACKGROUND Antiretroviral treatment (ART) options for young children co-infected with HIV and tuberculosis are limited in resource-poor settings due to limited data on the use of efavirenz (EFV). Using available pharmacokinetic data, an EFV dosing schedule was developed for young co-infected children and implemented as the standard of care at Macha Hospital in Southern Province, Zambia. Treatme...
متن کاملAntiretroviral Treatment in Resource-Limited Settings 2012
1HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA 2Vaccine and Infectious Disease & Public Health Science Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA 3Departments of Global Health and Epidemiology, University of Washington, Seattle, WA 98109, USA 4 Infectious Diseases Section, AIDS Program, Yale University School of Medicin...
متن کاملProphylactic antiretroviral regimens for prevention of mother-to-child transmission of HIV in resource-limited settings.
PURPOSE OF REVIEW With the large international mobilization against HIV/AIDS, more HIV-infected people in resource-limited settings have access to antiretroviral therapy, including pregnant women. The relevance of simplified prophylactic antiretroviral regimens for the prevention of mother-to-child transmission of HIV may become questionable due to their lower efficacy and their higher risk of ...
متن کاملLaboratory monitoring to guide switching antiretroviral therapy in resource-limited settings: clinical benefits and cost-effectiveness.
BACKGROUND As second-line antiretroviral therapy (ART) availability increases in resource-limited settings, questions about the value of laboratory monitoring remain. We assessed the outcomes and cost-effectiveness (CE) of laboratory monitoring to guide switching ART. METHODS We used a computer model to project life expectancy and costs of different strategies to guide ART switching in patien...
متن کاملInfant outcomes after maternal antiretroviral exposure in resource-limited settings.
BACKGROUND AND OBJECTIVE The impact of maternal antiretrovirals (ARVs) during pregnancy, labor, and postpartum on infant outcomes is unclear. METHODS Infants born to HIV-infected mothers in ARV studies were followed for 18 months. RESULTS Between June 2006 and December 2008, 236 infants enrolled from Africa (n = 36), India (n = 47), Thailand (n = 152), and Brazil (n = 1). Exposure to ARVs i...
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ژورنال
عنوان ژورنال: Journal of Comparative Effectiveness Research
سال: 2012
ISSN: 2042-6305,2042-6313
DOI: 10.2217/cer.12.6